Pharmaceutical & Life Science industries require water, either for production or CIP, of the utmost quality: free of pathogens and chemicals such as chlorine & ozone. Aquafine® UV System could be used for:
This is the most common application of UV light in water treatment. Ultraviolet energy causes permanent inactivation of microorganisms by disrupting DNA so that they are no longer able to maintain metabolism or reproduce. A pharmaceutical water system could have several locations where UV equipment would be installed. Some typical locations of installation would be post-carbon filter and pre-RO (reverse osmosis). When installed downstream of the carbon bed and or directly upstream of the RO unit, a UV system can significantly reduce the microbial counts by destroying at least 99.9% of the bacteria present in the influent stream.
While the addition of chlorine and chloramines to city water may control bacteria levels, they have undesirable effects on the degradation of membrane filtration or RO. But popular methods of removal, such as carbon beds or chemical injection, have proven to be problematic. Sodium metabisulfite involves replacing one chemical with another and creates food for microorganisms, while carbon beds can be inefficient, vulnerable to channeling and provide breeding grounds for microorganisms. Aquafine pioneered the technology of chlorine and chloramines destruction utilizing UV light in the pre-Reverse Osmosis.
Ozone is commonly used in the pretreatment area of a water system, as well as for sanitizing process and re-circulating systems. Prior to the point-of-use, the residual ozone needs to be destroyed to ensure the process water is not compromised. After considering the appropriate variables, a properly sized UV unit can be guaranteed to destroy the ozone to non-detectable limits, insuring the integrity of the process and the product. A dosage of 90 mJ/cm2 is recommended for destruction of ozone residuals of 1.0ppm.
The USP 31 regulations require an upper limit of 500ppb for TOC for both USP Purified Water as well as for WFI (Water for Injection). Aquafine uses a powerful 185nm wavelength appropriately sized and designed to meet this application.
1. Aquafine offers validated systems providing UV lamp, NIST traceable UV sensor validation with certificates, & Bioassay amalgam technology
2. All systems comply with cGMP, FDA requirements, and sanitary connections conform to DIN and USDA 3A standards.
3. Aquafine has served the diverse of Pharmaceutical & Life Science industries for more than 60 years, with unmatched record of failure percentage is less than 0.05%.
4. Simple maintenance is delivered through self-locking mechanism on the SE (single ended) lamp base, making lamp change-outs easy.